Department of Public Health and Exercise Science

Exercise Science

  1. Home
  2. Exercise Science

Education

  • Doctor of Philosophy, Biomechanics & Movement Science, University of Delaware
  • Master of Science, Exercise Science / Sports Medicine, University of Delaware
  • Bachelor of Science, Athletic Training, Boston University

Teaching Specialties

  • Evaluation and treatment of athletic injuries and illnesses
  • Physiologic implications of injury
  • Utilizing evidence to guide clinical decision-making in sports medicine
  • Implementation of screening & treatment programs to reduce injury risk in clinical practice

Current Teaching

  • AT 5200 - Functional Human Anatomy
  • AT 5300 - Examination, Diagnosis, and Treatment I
  • AT 5350 - Physiology of Injury
  • AT 5570 - Clinical Inquiry I
  • AT 5690 - Athletic Training Clinical Experience III
  • AT 5830 - Applied Health & Prevention Strategies
  • AT 5970 - Clinical Inquiry II 
  • ES 5720 - Motor Behavior for Sport & Performance

Honors & Awards

  • Fellow, National Athletic Trainers' Association (2024)
  • Chancellor's Award for Excellence in Research, Scholarship, and Creative Activity (2024)
  • Distinguished Graduate Faculty (2024)
  • Beaver College of Health Sciences Research & Scholarly Endeavors Award (2021)
  • Board of Governors Appalachian State University School/College Teaching Award (2020)
  • Appalachian State University Graduate Studies Academy of Outstanding Mentors (2020)

Professional Affiliations / Organizations

  • Member, National Athletic Trainers Association
  • Member, American College of Sports Medicine
  • Certified Athletic Trainer (ATC)
  • North Carolina Licensed Athletic Trainer (LAT)
  • Certified Strength & Conditioning Specialist (CSCS)

Laboratory Affiliation

Research Interests

  • Neuromechanical implicatons of joint injuries
  • Impact of attention and cognition on joint stability
  • Central nervous system adaptations to training and rehabilitation
  • Data processing & analysis in exercise science & sports medicine

Selected Publications

  • Needle AR, Howard JS, Downing MB, Skinner JW. Neural-Targeted Rehabilitation Strategies to Restore Typical Activation after Joint Injury. J Athl Train; 2024. In Press.
  • Kim KM, Needle AR, Kim JS, An YW, Cruz-Diaz D, Taube W. Disinhibitory Interventions for Chronic Ankle Instability: A systematic review with meta-analysis. Disabil Rehabil; 2024. 46(2):241-256.
  • Needle AR, Tinsley JE, Cash JJ, Koeval BK, Barton JA, Howard JS. The effects of neuromuscular electrical stimulation to the ankle pronators on neural excitability & functional status in patients with chronic ankle instability. Phys Ther Sport; 2023. 60:1-8.
  • Bruce AS, Howard JS, van Werkhoven H, McBride JM, Needle AR. The effects of transcranial direct current stimulation on chronic ankle instability. Med Sci Sport Exerc. 2020; 52(2):335-344. 
  • Needle AR, Rosen AB. Why re-think injury rehabilitation? Athl Train Sport Health Care. 2020; 12(6):243-244.
  • Kaminski TW, Needle AR, Delahunt EA. Prevention of Lateral Ankle Sprains. J Athl Train. 2019. 54(6):650-661.
  • Burcal CJ, Needle AR, Custer LC, Rosen AB. The effects of cognitive loading on motor behavior in injured individuals: a systematic review. Sports Med. 2019. In press.
  • Stirling AM, McBride JM, Merritt EK, Needle AR. Nervous system excitability and joint stiffness following short-term dynamic ankle immobilization. Gait Posture. 2018;59(Supplement C):46-52.
  • Rosen AB, Needle AR, Ko J. Ability of Functional Performance Tests to Identify Individuals With Chronic Ankle Instability: A Systematic Review With Meta-Analysis. Clin J Sport Med. 2017;In Press
  • Needle AR, Lepley AS, Grooms D. Evidence of Neurological Adaptation after Ligamentous Injury: A summary of assessment, findings, and clinical interpretation.  Sports Med. 2017. 47(7): 1271-1288.
  • Kim AS, Needle AR, Thomas SJ, Higginson CI, Kaminski TW, Swanik CB. A sex comparison of reactive knee stiffness under cognitive loads. Clin Biomech (Bristol, Avon). 2016; 35: 86-92. 
  • Needle AR, Swanik CB, Baumeister J, Schubert M, Reinecke K, Higginson JS, Farquhar WB, Kaminski TW, Higginson JS. Decoupling of Laxity & Cortical Activation in Unstable Ankles during Ligamentous Loading. Eur J Appl Phys. 2014; 114:2129-2138.
  • Needle AR, Baumeister J, Kaminski TW, Farquhar WB, Higginson JS, Swanik CB. Neuromechanical coupling in the regulation of muscle tone and joint stiffness. Scand J Med Sci Sport. 2014; 24 (5): 737-748.
  • Needle AR, Palmer JA, Kesar TM, Binder-McLeod SA, Swanik CB. Brain regulation of muscle tone in healthy and functionally unstable ankles. J Sport Rehab. 2013; 22(3):202-11.

My NCBI Bibliography

ResearchGate Profile

Google Scholar Profile

Title: Professor, PhD, Biomechanics and Movement Science, Graduate Faculty

Email address: Email me

Phone: (828) 262-4039

Fax: (828) 262-3138

Office address
Leon Levine Hall 422

Education

  • Ph.D., Auburn University
    • Program: Kinesiology
    • Concentration: Exercise Physiology
  • M.S., University of Wisconsin-La Crosse
    • Program: Human Performance
    • Concentration: Applied Sport Science
  • B.S., University of Wisconsin-Green Bay
    • Major: Human Biology
    • Concentration: Exercise Science

Current Teaching

  • ES 2005 – Introduction to Physiological Assessment
  • ES 3002 – Exercise Physiology

Professional Affiliations/Organizations

  • American Physiological Society
  • American College of Sports Medicine

Laboratory Affiliation

Research Interests

  • Biomarkers of concussion injury
  • Lactate metabolism

Publications

https://pubmed.ncbi.nlm.nih.gov/?term=Rogatzki%20MJ&sort=date

Title: Assistant Professor, PhD, Kinesiology, Graduate Faculty

Email address: Email me

Phone: (828) 262-7986

Fax: (828) 262-3138

Office address
Leon Levine Hall 435

Education

  • 2001-2006 East Carolina University - Greenville, NC
    • Department of Exercise and Sport Science
    • Ph.D. Bioenergetics
    • Mentor: G. Lynis Dohm Ph.D., Department of Physiology
    • Dissertation Title: The Role of PKCBeta in Skeletal Muscle Insulin Resistance.
  • 1999-2001 California State University, Chico Chico, CA
    • Department of Kinesiology
    • M.A. Physical Education (emphasis in Exercise Physiology)
    • Mentor: John (Jack) Azevedo Ph.D.
    • Thesis Title: Correlation of Glucose Transport and GlucoseTransporter Protein in Human Skeletal Muscle.
  • 1994-1999 California State University, Chico Chico, CA
    • Department of Physical Education and Exercise Science
    • B.S. Exercise Physiology

Teaching Specialties

  • Obesity Prevention, Chronic and Infectious Disease, Rural Public Health, Exercise Physiology and Prescription, and Emergency Response & CPR

Current Courses Being Taught

  • Introduction to Public Health (PH 2000)
  • Emergency Care and CPR (PH 3100)
  • Obesity Prevention (PH 4400)
  • Seminar in Rural Public Health (PH 4650)

Previous Teaching

  • Fitness in Health Promotion (HP 3000)
  • Biostatistics (HP 4100)
  • Epidemiology (HP 4200)
  • Weight Mangaement (HP 4400)

Professional Affiliations

  • American Public Health Association (APHA)
  • American Red Cross

 Community Affiliations

  • Watauga Housing Council Volunteer
  • Hunger and Health Coalition Volunteer 

Research Interests

  • Obesity and Insulin Resistance

Publications and Presentations

  • R. Andrew Shanely, Jennifer J. Zwetsloot, Thomas J. Jurrissen, Lauren T. Carson, Kevin A. Zwetsloot, Alan R. Needle, Anna E. Bishop, Guoyao Wu, and Penelope Perikns-Veazie. Daily watermelon consumption decreases plasma sVCAM-1 levels in overweight and obese postmenopausal women. Journal of Nutrition Research. 2020 Apr;76:9-19.
  • Bouldin ED, Vandenberg A, Roy M, Hege A, Zwetsloot JJ, Howard JS. Prevalence and domains of disability within and outside Appalachian North Carolina: 2013-2016 BRFSS. Disability and Health Journal. 2020 Apr;13(2).
  • Sharaievska I, Battista RA, Zwetsloot J, Use of Physical Activity Monitoring Devices by Families in Rural Communities: Qualitative Approach. JMIR Pediatr Parent 2019;2(1):e10658. 
  • Jennifer J. Zwetsloot, Rebecca A. Battista, Kristopher Hartley, Chris Demczar, Alanna Young, and Erica Larson. Reducing attrition and improving program adherence in a physician-referred weight loss program for adults. Medicine & Science in Sports & Exercise. May 2018.
  • Jennifer J. Zwetsloot, Lindsey Miller, Barrett Ward, Christina Gilboy, Hannah McGlamery. The Acute Resting Metabolic Response to Energy Deficit caused by Increased Expenditure vs. Caloric Restriction. Medicine & Science in Sports & Exercise. 47(5S):639, May 2015.
  • Zwetsloot, J.J., E.B. Tapscott, P. Buttrick, M. Leitges, G.L. Dohm.  PKC beta knockout blocks insulin stimulated IRS1ser307 phosphorylation.  Experimental Biology 2006, San Francisco, CA.  FASEB, (Abstract Supplement), #209.13, 2006.
  • John P. Thyfault, Melaine G.-Cree, Jill A. Bell, Jennifer J. Zwetsloot, Timothy R. Koves, Robert R. Wolfe, Deborah M. Muoio and G.L. Dohm.  The impact of obesity, muscle contraction, and insulin on skeletal muscle lipids: a lipidomics approach.  Integrative Biology of Exercise, 2006. 
  • Zwetsloot, J.J., D. Zheng, W. Pories, K. MacDonald, and G.L. Dohm.  Link between PKCb and IRS-1 serine phosphorylation in obese human skeletal muscle.  American Diabetes Association Annual Meeting 2005, San Diego, CA.  Diabetes, 54 (Supplement 1), A324, #1335-P,  2005.
Title: Senior Lecturer, PhD, Bioenergetics, Director, Departmental Honors in Public Health, Graduate Faculty (Affiliate), Vice Chair of Faculty Senate

Email address: Email me

Phone: (828) 262-6800

Fax: (828) 262-3138

Office address
Leon Levine Hall 428

Education

  • Post-doctoral research fellowship - University of Missouri, Columbia
  • Ph.D. in Bioenergetics - East Carolina University
  • M.A. in Physical Education - California State University, Chico
  • B.S. in Exercise Physiology - California State University, Chico

Current Teaching

  • ES 2035 - Introduction to Human Anatomy & Physiology
  • ES 3002 - Exercise Physiology
  • ES 3003 - Exercise Physiology Laboratory
  • ES 5624 - Physiology of Exercise

Professional Affiliations / Organizations

  • American Physiological Society
  • American College of Sports Medicine

Laboratory Affiliation

Research Interests

  • My primary scholarly interests include investigating the mechanisms responsible for sarcopenia (the age-related loss of skeletal muscle mass and strength) and skeletal muscle repair/regeneration after injury. My laboratory seeks to develop exercise and/or nutritional interventions for the treatment/prevention of sarcopenia and enhanced recovery of skeletal muscle from damage.
  • Furthermore, my laboratory focuses on the role inflammation plays in sarcopenia and the failed regrowth from atrophy in aged skeletal muscle, as well as in skeletal muscle repair and regeneration after injury.
  • Additionally, my laboratory investigates the role of exercise on the composition and diversity of the gut microbiome.

Current research projects include:

  • Phytoecdysteroid supplementation on growth and function characteristics in young and old skeletal muscle in response to resistance and endurance exercise
  • Phytoecdysteroid supplementation on the recovery of function and structural characteristics in young and old skeletal muscle in response to eccentric contraction-induced injury
  • Influence of exercise on the composition, diversity, and function of the gut microbiota in young and aging subjects
  • Effect of exercise on the recolonization and function of the gut microbiota after a course of antibiotics

Selected Publications

Google Scholar link for all publications

# - denotes student trainee

  • Zwetsloot, K.A., L.M. Westerkamp, B.F. Holmes, and T. P. Gavin. “AMPK regulates basal skeletal muscle capillarization and VEGF expression, but is not necessary for the angiogenic response to exercise.” Journal of Physiology. 586(24). 6021-6035. 2008. doi: 10.1113/jphysiol.2008.159871
  • Zwetsloot, K.A.*, A. Nedergaard*, T.E. Childs, and F.W. Booth. “Differences in transcriptional patterns of extracellular matrix, inflammatory, and myogenic regulatory genes in myofibroblasts, fibroblasts, and muscle precursor cells isolated from old male rat skeletal muscle using a novel cell isolation procedure.” Biogerontology. 13(4). 383-398. 2012. * - denotes authors contributed equally to this work. doi: 10.1007/s10522-012-9382-7
  • Zwetsloot, K.A., T.E. Childs, L.T. Gilpin, and F.W. Booth. “Zero-passaged muscle precursor cells from old skeletal muscle have delayed proliferation and differentiation.” Cell Proliferation. 46(1). 45-57. 2013. doi: 10.1111/cpr.12007
  • Zwetsloot, K.A., C.S. John#, M.M. Lawrence#, R.A. Battista, and R.A. Shanely. “High intensity interval training induces a modest inflammatory response in young active men.” Journal of Inflammation Research. 7. 9-17. 2014. doi: 10.2147/JIR.S54721
  • Shanely, R.A., K.A. Zwetsloot, N.T. Triplett, M.P. Meaney, G.E. Farris, and D.C. Nieman. “Human skeletal muscle biopsy procedures using the modified Bergström technique.” Journal of Visualized Experiments. (91) e51812. 2014.  doi:10.3791/51812
  • Zwetsloot, K.A., R.A. Shanely, E.K. Merritt, and J.M. McBride. Invited Review: “Phytoecdysteroids: A Novel, Non-Androgenic Alternative for Muscle Health and Performance.”  Journal of Steroids & Hormonal Science. 12:e001. 2014. doi: 10.4172/2157-7536.S12-e001
  • Godwin, J.S.#, C.F. Hodgman#, A.R. Needle, K.A. Zwetsloot, and R.A. Shanely. Whole-body Heat Shock Accelerates Recovery from Impact-Induced Skeletal Muscle Damage in Mice. Conditioning Medicine. 2(4): 184-191. August 2020. http://www.conditionmed.org/Data/View/9543?type=300
  • Nieman, D.C., K.A. Zwetsloot, A.J. Simonson, A.T. Hoyle, X. Wang, H.K. Nelson, C. Lefranc-Millot, and L. Guerin-Deremaux. Effects of Whey and Pea Protein Supplementation on Post-Eccentric Exercise Muscle Damage: A Randomized Trial. Nutrients. 12(8): 2382. August 2020. doi: 10.3390/nu12082382
  • Lawrence, M.M.#, K.A. Zwetsloot, S.T. Arthur, C.A. Sherman#, J.R. Huot, V. Badmaev, M. Grace, M.A. Lila, D.C. Nieman, and R.A. Shanely. Phytoecdysteroids Do Not Have Anabolic Effects in Skeletal Muscle in Sedentary Aging Mice. International Journal of Environmental Research and Public Health - Special Issue: Regulation of Muscle Mass, Exercise, and Metabolism. 18, 370. January 2021.  doi: 10.3390/ijerph18020370
  • Zwetsloot, K.A., R.A. Shanely, J.S. Godwin#, and C.F. Hodgman#. Phytoecdysteroids Accelerate Recovery of Skeletal Muscle Function Following in vivo Eccentric Contraction-Induced Injury in Adult and Old Mice. Frontiers in Rehabilitation Sciences - Exercise and Aging with Musculoskeletal Conditions. 2. 1-13. November 2021. doi: 10.3389/fresc.2021.757789
  • Koopmans, P.J.# and K.A. Zwetsloot. A simple and inexpensive running wheel model for progressive resistance training in mice. Journal of Visualized Experiments. (182), e63933, April 2022. doi:10.3791/63933
  • Stewart, J.A.#, E.K. Merritt, D.E. Lidstone, J.M. McBride, and K.A. Zwetsloot. Prolonged cycling lowers subsequent running mechanical efficiency in collegiate triathletes. BMC Sports Science, Medicine, and Rehabilitation. 14(149). August 2022. doi: 10.1186/s13102-022-00543-w
  • Koopmans, P.J.#, T.K. Williams-Frey#, and K.A. Zwetsloot. "Stuart has got the PoWeR! Skeletal muscle adaptations to a novel heavy progressive weighted wheel running exercise model in C57BL/6 mice." Experimental Physiology. 109:271-282.October 2023. doi.org/10.1113/EP091494
  • Koopmans, P.J.#, K.A. Zwetsloot, and K.A. Murach. Invited Review: “Going Nuclear: Molecular adaptations to exercise mediated by myonuclei” - Special Issue: "Molecular Mechanisms of Exercise-Induced Skeletal Muscle Health”; Sports Medicine and Health Science. 5.1. March 2023. doi: 10.1016/j.smhs.2022.11.005
  • Brooks, C.N., M.E. Wight#, O.E. Azeez#, R.M. Bleich, and K.A. Zwetsloot. Invited Review: “Growing old together: What we know about the influence of diet and exercise on the aging host’s microbiome.” Frontiers in Sports and Active Living. 5:1168731. April 2023. doi: 10.3389/fspor.2023.1168731
Title: Professor, PhD, Bioenergetics, Graduate Faculty

Email address: Email me

Phone: (828) 262-7281

Fax: (828) 262-3138

Office address
Leon Levine Hall 412C

Education

  • Ph.D. in Kinesiology (Biomechanics), The Pennsylvania State University, 2014
  • M.S. in Kinesiology (Biomechanics), The Pennsylvania State University, 2008
  • B.Soc.Sci. in Sports Psychology, The University of Pretoria (South Africa), 2004
  • B.Eng. in Electrical Engineering, The University of Pretoria (South Africa), 1998

Current Teaching

  • ES 3550 – Introduction to Biomechanics
  • ES 5591 – Biomechanical Laboratory Assessment

Professional Affiliations / Organizations

  • American Society of Biomechanics

Laboratory Affiliation

Research Interests

  • Novel motion analysis techniques to assess movement outside the traditional laboratory

Selected Publications

  • Hawley, VS, Gurchiek, RD, van Werkhoven, H. (2022). Can foot anthropometry predict vertical jump performance? Journal of Strength and Conditioning Research, 36(7), 1860-1865.
  • Farina, KA, Needle AR, van Werkhoven, H. (2021). Continuous tracking of foot strike pattern during a maximal 800-meter run. Sensors, 21(17), 5782.
  • van Werkhoven, H, Farina, KA, Langley, MH. (2019). Using a soft conformable foot sensor to measure changes in foot strike angle during running. Sports, 7, 184.
  • Gurchiek, RD, McGinnis, RS, Needle AR, McBride, JM, van Werkhoven, H. (2018). An adaptive filtering algorithm to estimate sprint velocity using a single inertial sensor. Sports Engineering, 21, 389-399.
  • van Werkhoven, H, Piazza, SJ. (2017). Does foot anthropometry predict metabolic cost in running? Journal of Applied Biomechanics, 33, 317-322.
  • Gurchiek, RD, McGinnis, RS, Needle AR, McBride, JM, van Werkhoven, H. (2017) The use of a single inertial sensor to estimate 3-dimensional ground reaction force during accelerative running tasks. Journal of Biomechanics, 61, 263-268.
Title: Associate Professor, PhD, Biomechanics, Graduate Faculty

Email address: Email me

Phone: (828) 262-7120

Fax: (828) 262-3138

Office address
Leon Levine Hall 412D

Education

  • Ph.D., The Pennsylvania State University, 1995
    Major: Physiology of Exercise
  • Ph.D. Dissertation: The Effects of Exercise-Related Peptide F Elevation on Human B-Cell Activation
  • M.S., Appalachian State University, 1989
    Major: Exercise Science
  • B.S., Wake Forest University, 1987
    Major: Health & Sport Science
    Minor: Biology

Teaching Specialties

  • Theoretical and Practical Aspects of Strength and Conditioning
  • Neuromuscular and Endocrine Exercise Physiology
  • Aging and Physical Activity

Current Teaching

  • Theoretical Principles of Strength and Conditioning (Graduate)
  • Analysis of Sport Performance (Graduate)
  • Human Physiology Laboratory (Undergraduate)
  • Exercise Physiology (Undergraduate)

Professional Affiliations / Organizations

  • American College of Sports Medicine (1987-2018)
  • American Society of Phlebotomy Technicians (1988-1989)
    • Certified Phlebotomist; General Venipuncture/Catheterization
  • National Strength and Conditioning Association (1988-present)
    • Fellow
    • President of the Board of Directors, 2018-2021
    • Certified Strength and Conditioning Specialist with Distinction
  • USA Weightlifting (1992-2023)
    • Certified Level 1 Coach

Laboratory Affiliations

Publications

Book Chapters

  • Heikkinen D and Triplett NT. Movement Preparation.  NSCA’s Guide to Tests and Assessments (M.T. Jones, ed.), Human Kinetics, Champaign, IL, 2024 (in press).
  • Shaw I, Triplett T, and Shaw BS. Resistance Training and Weight Management: Rationale and Efficacy. Weight Management: Challenges and Opportunities (H.M. Heshmati, ed.), InTech Open, 2022. DOI: http://dx.doi.org/10.5772/intechopen.101840
  • Triplett NT. Advanced Program Options. ACSM’s Resources for the Personal Trainer (6th edition, T. Musto, ed.), Lippincott Williams & Wilkins, Philadelphia, PA, pp. 499-523, 2021.
  • Grieco C and Triplett NT. Bioenergetics. NSCA’s Essentials of Personal Training (3rd edition, B. Schoenfeld and R. Snarr, eds.), Human Kinetics, Champaign, IL, pp. 27-40, 2021.

 

Selected Journal Articles (last 5 years)

  • Comfort P, McMahon JJ, Lake JP, Ripley NJ, Triplett NT, and Haff GG.  Relative strength explains the differences in multi-joint rapid force production between sexes.  PlosOne 19(2), e0296877, 2024.
  • Fiedler MJ, Triplett NT, Hamilton KC, Needle AR, van Werkhoven H.  The effect of different weight plates (bumper versus standard) on the biomechanics of the bench press.  Journal of Strength and Conditioning Research 38(4), e1430149, 2024.
  • Gaynor-Metzinger SHA, Triplett NT, Meucci M, Fasczewski KS, Flinchum DH, and Collier SR.  Central arterial stiffness, wave reflection, and heart rate variability following 4-week high-intensity resistance training intervention in young active women.  European Journal of Applied Physiology 122, 2283-2293, 2022. https://doi.org/10.1007/s00421-022-05003-4
  • Chapman M, Larumbe-Zabala E, Triplett NT, and Naclerio F.  Velocity change estimation by subjective measures over a wide-load spectrum in squat and bench press. Journal of Strength and Conditioning Research 35 (2S), S51-S56, 2021.
  • Hornsby WG, Haff GG, Suarez DG, Ramsey MW, Triplett NT, Hardee JP, Stone ME, and Stone MH.  Alterations in Adiponectin, Leptin, Resistin, Testosterone and Cortisol across Eleven Weeks of Training among Division One Collegiate Throwers: A Preliminary Study.  Journal of Functional Morphology and Kinesiology 5, 44, 2020.
  • Chapman M, Larumbe-Zabala E, Goss-Sampson M, Triplett NT, and Naclerio F. Using perceptual and neuromuscular responses to estimate mechanical changes during continuous sets in the bench press. Journal of Strength and Conditioning Research 33(10), 2722-2732, 2019.
  • Chapman M, Larumbe-Zabala E, Goss-Sampson M, Colpus M, Triplett NT, and Naclerio F. Perceptual, mechanical, and electromyographic responses to different relative loads in the parallel squat. Journal of Strength and Conditioning Research 33(1), 8-16, 2019.
Title: Professor, PhD, Physiology of Exercise, Exercise Science Undergraduate Program Director, Graduate Faculty

Email address: Email me

Phone: (828) 262-7148

Fax: (828) 262-3138

Office address
Leon Levine Hall 432C

Education

  • Postdoctoral Research Fellow, The Pennsylvania State University, 2010-2013
    • Specialization: Thermal and microvascular physiology
  • Ph.D. Loughborough University (United Kingdom), 2005-2009
    • Specialization; Thermal Physiology
  • B.Sc. (Hons) Human Biology, Loughborough University (United Kingdom), 2002-2005

Current Teaching

  • ES 2050: Human Physiology
  • ES 4300: Environmental Physiology

Professional Affiliations

  • American Physiological Society
  • American Heart Association
  • American College of Sports Medicine

Laboratory Affiliation

  • Thermal and Microvascular Physiology Laboratory  (Director)

Research Interests

Dr. Smith is Director of the Thermal and Microvascular Physiology Laboratory which focuses on human thermoregulation and physiological responses to environmental stressors.  Current research includes utilizing novel approaches, including microdialysis and laser Doppler flowmetry, for assessing dermal carcinogen absorption and elucidating key factors modulating absorption during occupational exposure in firefighters. Understanding carcinogen exposure routes is of fundamental importance in various occupational settings to inform risk mitigation strategies and improve long term health outcomes. Additonal ongoing lines of investigation include examining in vivo signaling mechanisms underlying thermoregulatory and microvascular dysfunction in primary aging and cardiovascular disease groups.

Selected Research Publications 

For a complete list of publications: https://www.ncbi.nlm.nih.gov/myncbi/1J9H8tsT6Qz5V/bibliography/public/

  • Kasey Klieber, Caroline  J. Smith, Steven D Beck, Adam Hege, Makenzie G Corgan, Crystal A West, Lainey Hunnicutt, Scott R Collier. Familiarization with ambulatory sleep and blood pressure monitoring is necessary for representative data collection. Physiological Reports, October 2023. doi.org/10.14814/phy2.15843
  • Wait, S.O., Charkoudian, N., Skinner, J.W., Smith, C.J. (2023). Combining hypoxia with thermal stimuli in humans: physiological responses to complex environments. Am J Physiol. Reg Integr Comp Physiol. 324(6): R677-R690.
  • Margaret C. Morrissey, Douglas J. Casa, Gabrielle J. Brewer, William M. Adams, Yuri Hosokawa, Courteney L. Benjamin, Andrew J. Grundstein, David Hostler, Brendon P. McDermott, Meredith L. McQuerry, Rebecca L. Stearns, Erica M. Filep, David W. DeGroot, Juley Fulcher, Andreas D. Flouris, Brenda L. Jacklitsch, John F. Jardine, Rebecca M. Lopez, Ronda B. McCarthy, Yannis Pitisladis, Riana R. Pryor, Zachary J. Schlader, Caroline J. Smith, Denise L. Smith, June T. Spector, Jennifer K. Vanos, W. Jon Williams, Nicole T. Vargas, Susan W. Yeargin. (2021). Heat Safety in the Workplace: Modified Delphi Consensus to Establish Strategies and Resources to Protect U.S Workers. GeoHealth 1;5(8): e2021GH000443.
  • Sui, X., Terán, J. E., Feng, C., Wustrow, K., Smith, C.J. Vinueza, N. R. (2020). Quantification of anthracene after dermal absorption test via APCI-tandem mass spectrometry. Analytical Methods. doi.10.1039/D0AY00486C 
  • Collier SR, McCraw C, Campany M, Lubkeman A, StClair P, Ji H, Sandberg K, Morgan J., Smith C.J. (2020). Comparison of Withings Body Cardio to Gold Standard Measurements of Pulse-Wave Velocity and Body Composition. J Pers Med. 10(1): 17.
  • Smith, C.J. (2019). Pediatric Thermoregulation: Considerations in the Face of Global Climate Change. Nutrients, 26;11(9). doi: 10.3390/nu11092010.
  • Smith, C.J. and Havenith, G. (2019). Upper body sweat mapping provides evidence of relative sweat redistribution towards the periphery following hot-dry heat acclimation.Temperature. 7;6(1):50-65. doi: 10.1080/23328940.2019.1570777.
  • Smith CJ, Craighead DH, Alexander LM. (2017). Effects of vehicle microdialysis solutions on cutaneous vascular responses to local heating. J Appl Physiol. doi: 10.1152/japplphysiol.00498.2017. [Epub ahead of print]
  • Craighead, D.H., Smith, C.J., and Alexander, L.M. (2017). Blood pressure normalization via pharmacotherapy improves cutaneous microvascular function through NO-dependent and independent-medchanisms. Microcirculation. 2017 Oct; 24(7). doi: 10.1111/micc.12382.]
  • Smith C.J. and Johnson, J. (2016). Responses to hyperthermia. Optimizing heat dissipation by convection and evaporation: Neural control of skin blood flow and sweating in humans. Auton Neurosci. 196: 25-36
  • Alley, J.R., Mazzochi, J.W., Smith, C.J., Morris, D.M., and S.R. Collier. (2015). Effects of exercise timing on sleep architecture and nocturnal blood pressure. J Strength Cond Res.29(5): 1378-1385
  • Smith, C.J., Alexander, L.M., and W.L. Kenney. (2013). Non-Uniform, Age-Related Decrements in Regional Sweating and Skin Blood Flow. Am J Physiol Regul Integr Comp Physiol. 305(8): R877-R88
  • Smith, C.J., Santhanam, L., and L.M. Alexander. (2013). Rho-Kinase activity and cutaneous vasoconstriction is upregulated in essential hypertensive humans. Microvasc Res.87: 58-64
  • Smith, C.J., Kenney, W.L., and L.M. Alexander. (2013). Regional relation between skin blood flow and sweating to passive heating and local administration of acetylcholine in young, healthy humans. Am J Physiol Regul Integr Comp Physiol. 304: R566-R573
  • Smith, C.J., Machado-Moreira, C.A., Plant, G., Hodder, S., Havenith, G. and N.A.S. Taylor. (2012). Design Data for Footwear - Sweating Distribution on the Human Foot. Int. J. Clothing Science and Technology. 25(1): 43-58
  • Smith, C.J. and G. Havenith. (2012). Body Mapping of Sweating Patterns in Athletes: A Sex Comparison. Med Sci Sports Exerc. 44(12): 2350-2361
  • Bruning, R.S., Santhanam, L., Stanhewicz, A.E., Smith, C. J., Berkowitz, D.E., Kenney W.L., and L.A. Holowatz. (2012). Endothelial nitric oxide synthase mediates cutaneous vasodilation during local heating and is attenuated in middle-aged human skin. J Appl Physiol. 112: 2019-2026
  • Stanhewicz, A.E., Bruning, R.S., Smith, C.J., Kenney, W.L., and L.A. Holowatz. (2012). Local tetrahydrobiopterin administration augments reflex cutaneous vasodilation through nitric oxide-dependent mechanisms in aged human skin. J Appl Physiol. 112: 791-797
  • Smith, C.J., Santhanam, L., Bruning, R.S., Stanhewicz, A.E., Berkowitz, D.E., and L.A. Holowatz. (2011). Upregulation of iNOS contributes to attenuated eNOS-dependent cutaneous vasodilation in essential hypertensive humans. Hypertension. 58: 935-942
  • Smith, C.J., and G. Havenith. (2011). Body mapping of sweating patterns in male athletes in mild exercise induced hyperthermia. Eur J Appl Physiol. 111(7): 1391-1404
  • Havenith, G., Fogarty, A., Bartlett, B., Smith, C.J., and V. Ventenat. (2008). Male and female upper body sweat distribution during running measured with technical absorbents. Eur J Appl Physiol. 104: 245-255
Title: Associate Professor, PhD, Thermal Physiology, Graduate Faculty

Email address: Email me

Phone: (828) 262-8450

Fax: (828) 262-3138

Office address
Leon Levine Hall 406

Education

  • Postdoctoral Fellowship - University of Missouri, Columbia
    July 2006
  • Doctor of Philosophy - University of Florida, Gainesville, FL
    Emphasis: Exercise Physiology
    December 2002
  • Master of Arts in Exercise Science - Northern Arizona University, Flagstaff, AZ
    Emphasis: Exercise Physiology
    December 1996
  • Bachelor of Science in Physical Education - California State University Fullerton, Fullerton, CA
    January 1993

Teaching Specialties

  • Exercise Physiology
  • Muscle Biology
  • Respiratory Physiology

Current Teaching

  • ES 3002 Exercise Physiology
  • ES 3003 Exercise Physiology Laboratory 
  • ES 3005 Advanced Physiological Assessment
  • ES 5622 Skeletal Muscle Physiology 

Professional Affiliations / Organizations

  • American Physiological Society
  • American College of Sports Medicine
  • American College of Sports Medicine, Southeastern Chapter
  • Public Responsibility in Medicine & Research

Laboratory Affiliation

  • Integrative Muscle Physiology Lab
  • Neuromuscular Laboratory

Research Interests

My research objective is to understand molecular and cellular regulation of skeletal muscle physiology and health across the life span.  

  • Sarcopenia (the age related loss of skeletal muscle mass and function)
  • Skeletal muscle atrophy
  • Inactivity-induced oxidative stress 
  • Exercise-induced muscle damage
  • Skeletal muscle density and its relation to health 

Current Research Project

  • Examining the relationship between skeletal muscle strength, power and intramuscular fat in healthy adults

 

Selected Publications 

Click to view my publications via Google Scholar

Title: Professor, PhD, Exercise Physiology, Graduate Faculty

Email address: Email me

Phone: (828) 262-6319

Fax: (828) 262-3138

Office address
Leon Levine Hall 412B

Education

  • Post-Doctoral Fellowship, 1999
    University of Jyvaskyla (Finland), Neuromuscular Research Center
    Major field of study: Biomechanics
  • Ph.D., Southern Cross University (Australia), 1999
    School of Exercise Science and Sport Management
    Major field of study: Human Movement Studies
  • M.S., The Pennsylvania State University, 1995
    Department of Exercise and Sport Science
    Major field of study: Exercise Physiology
  • B.S., West Virginia University, 1993
    Department of Physical Education
    Major field of study: Exercise Physiology

Teaching Specialties

  • Biomechanics

Current Teaching

  • ES 3550 Introduction to Biomechanics
  • ES 5591 Biomechanical & Physiological Laboratory Assessment
  • ES 5710 Biomechanics

Professional Affiliations / Organizations

  • National Strength & Conditioning Association

Laboratory Affiliation

Research Interests

  • Muscle Strength & Power, Athletic Performance, Stretch-Shortening Cycle

Recent Publications

  • McBride, J.M. Muscle actuators, not springs, drive maximal effort human locomotive performance. Journal of Sports Science and Medicine, Volume 20, Issue 4, 766-777, 2021.
  • Mcbride, J.M., S. Nimphius. Biological system algorithm reflected in sub-system joint work distribution movement strategies: Influence of strength and eccentric loading, Scientific Reports, Volume 10, Issue 1, 12052, 2020.
  • Maroto-Izquierdo, S., I. Gonzalez-Diez, D. Garcia-Lopez, J.M. Mcbride, J. Gonzalez-Gallego, J.A. Depaz. Comparison of flywheel and pneumatic training on hypertrophy, strength and power in professional handball players, Research Quarterly For Exercise And Sport, Volume 15, Pages 1-15, 2020.
  • Gurchiek, R.D., H. Rupasinghe, L. Watagoda, R.S. Mcginnis, H. Van Werkhoven, A.R. Needle, J.M. Mcbride, A.T. Arnholt. Sprint assessment using machine learning and a wearable accelerometer. Journal Of Applied Biomechanics, Volume 24, Pages 1-16, 2019.
Title: Professor, PhD, Human Movement Studies, Graduate Faculty

Email address: Email me

Phone: (828) 262-6333

Fax: (828) 262-3138

Office address
Leon Levine Hall 412A

Education

  • Ph.D. 2015 Kinesiology, Nutrition, and Rehabilitation, University of Illinois at Chicago, Chicago, IL
  • M.S. 2010 Exercise Science, Appalachian State University, Boone, NC
  • B.S. 2004 Biology, University of Toledo, Toledo, OH

Current Teaching

  • ES 4660 - Exercise Prescription for Clinical Populations
  • ES 5620 - Advanced Cardiorespiratory Physiology
  • ES 5635 - Electrocardiographic Interpretation
  • ES 5645 - Current Trends in Cardiopulmonary Pathophysiology
  • ES 5660 - Exercise Prescription & Chronic Disease Management

Professional Affiliations/Organizations

  • American College of Sports Medicine - Clinical Exercise Physiologist (CEP) Certified
  • American College of Sports Medicine, Southeast Chapter
  • American Physiological Society
  • Organization for the Study of Sex Differences
  • North American Artery Society
  • American Heart Association

Laboratory Affiliation

Research Interests

  • Cardiovascular disease prevention in high risk populations
  • Sex differences and effects of aging on cardiovascular function
  • Exercise and endothelial function
  • Oxidative stress and disease

Selected Publications

View all: Pubmed

  • Addressing Physical Inactivity in Aging, Rural Communities. Kappus RM. J Clin Exerc Physiol.  (2024) 13 (1): 18–21.
  • Healthy Aging: The Role of Physical Activity in Optimizing Cardiovascular Health. Kappus RM, Kowalski RJ. JIHHS, 3(1). 2023.
  • The Impact of COVID-19 on Cardiovascular Health Behaviors in Student Veterans. Canjar MR, Richard DL, Kappus RM. Nutrition, Metabolism and Cardiovascular Diseases. 2022 Mar;32(3):727-733. 
  • The feasibility of a novel method of bystander CPR training: A pilot study. Kappus RM, McCullough G. Am J Emerg Med. 2020 Mar;38(3):594-597.
  • Effect of oxidative stress on racial differences in vascular function at rest and during hand grip exercise. Kappus RM, Bunsawat K, Brown MD, Phillips SA, Haus JM, Baynard T, Fernhall B. J Hypertens. 2017 Jun 7. 
  • Racial Differences in Endothelial Function Following Antioxidant Supplementation. Kappus RM, Bunsawat K, Rosenberg AJ, Fernhall B. Int J Sports Med 2017 Feb 20.
  • Sex Differences in Autonomic Function Following Maximal Exercise. Kappus RM, Ranadive SM, Yan H, Lane-Cordova AD, Cook MD, Sun P, Harvey IS, Wilund KR, Woods JA, Fernhall B. Biology of Sex Differences. 2015 Dec 1;6:28.
  • Effect of Aspirin Supplementation on Hemodynamics in Older Firefighters. Lane-Cordova AD, Ranadive SM, Yan H, Kappus RM, Sun P, Bunsawat K, Smith DL, Horn GP, Ploutz-Snyder R, Fernhall B. Med Sci Sports Exerc. 2015 Dec;47(12):2653-9
  • Caffeine delays autonomic recovery following acute exercise. Bunsawat K, White DW, Kappus RM, Baynard T. Eur J Prev Cardiol. 2015 Nov;22(11):1473-9
  • Sex Differences in Ventricular-Vascular Coupling Following Endurance Training. Lane AD, Ranadive SM, Yan H, Kappus RM, Cook MD, Wilund K, Woods J, Fernhall B. European Journal of Applied Physiology. 2014 Dec;114(12):2597-606
  • Effect of Acute Moderate Exercise on Induced Inflammation and Arterial Function in Older Adults. Ranadive SM, Kappus RM, Cook MD, Yan H, Lane AD, Woods JA, Wilund KR, Iwamoto G, Vanar V, Tandon R, Fernhall B. Exp Physiol. 2014 Apr;99(4):729-39.
  • Hemodynamic and arterial stiffness differences between African-Americans and Caucasians following maximal exercise. Yan H, Ranadive SM, Heffernan KS, Lane AD, Kappus RM, Cook MD, Wu PT, Sun P, Harvey IS, Woods JA, Wilund KR, Fernhall B. Am J Physiol Heart Circ Physiol. 2014 Jan;306(1):H60-8.
  • Obesity and Overweight are Associated with Increased Carotid Diameter and Decreased Arterial Function in Young Otherwise Healthy Men. Kappus RM, Fahs CA, Smith D, Horn GP, Agiovlasitis S, Rossow L, Jae SY, Heffernan KS, Fernhall B. Am J Hypertension. 2013 Sep 18.
Title: Associate Professor, PhD, Kinesiology, Nutrition and Rehabilitation, Graduate Faculty

Email address: Email me

Phone: (828) 262-7214

Fax: (828) 262-3138

Office address
Leon Levine Hall 413